Knockout of serine-rich single-pass membrane protein 1 (Ssmem1) causes globozoospermia and sterility in male mice†
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منابع مشابه
Absence of the prion protein homologue Doppel causes male sterility.
The agent that causes prion diseases is thought to be identical with PrP(Sc), a conformer of the normal prion protein PrP(C). PrP(C)-deficient mice do not exhibit major pathologies, perhaps because they express a protein termed Dpl, which shares significant biochemical and structural homology with PrP(C). To investigate the physiological function of Dpl, we generated mice harbouring a homozygou...
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ژورنال
عنوان ژورنال: Biology of Reproduction
سال: 2020
ISSN: 0006-3363,1529-7268
DOI: 10.1093/biolre/ioaa040